Version 5.4
Homo sapiens Protein: MPPED2
Summary
InnateDB Protein IDBP-37195.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MPPED2
Protein Name metallophosphoesterase domain containing 2
Synonyms 239FB; C11orf8;
Species Homo sapiens
Ensembl Protein ENSP00000350833
InnateDB Gene IDBG-37191 (MPPED2)
Protein Structure
UniProt Annotation
Function Displays low metallophosphoesterase activity (in vitro). May play a role in the development of the nervous system (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity Expressed predominantly in fetal brain.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0007399 nervous system development
GO:0008152 metabolic process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR004843 Calcineurin-like phosphoesterase domain, apaH type
IPR029052 Metallo-dependent phosphatase-like
PFAM PF00149
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q15777
PhosphoSite PhosphoSite-
TrEMBL F2Z346
UniProt Splice Variant
Entrez Gene 744
UniGene Hs.606378
RefSeq NP_001575
HUGO HGNC:1180
OMIM 600911
CCDS CCDS7870
HPRD 02947
IMGT
EMBL AB209163 AL136088 AL353699 AL356240 BC031582 CH471064 U57911
GenPept AAC50564 AAH31582 BAD92400 EAW68256 EAW68257

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca