InnateDB Protein
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IDBP-372187.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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EXOG
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Protein Name
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endo/exonuclease (5'-3'), endonuclease G-like
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Synonyms
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ENDOGL1; ENDOGL2; ENGL; ENGL-a; ENGL-b; ENGLA; ENGLB;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000404305
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InnateDB Gene
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IDBG-26030 (EXOG)
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Protein Structure
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Function |
Endo/exonuclease with nicking activity towards supercoiled DNA, a preference for single-stranded DNA and 5'-3' exonuclease activity. {ECO:0000269PubMed:18187503}.
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Subcellular Localization |
Mitochondrion inner membrane {ECO:0000269PubMed:18187503}.
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Disease Associations |
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Tissue Specificity |
Ubiquitous.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001604
DNA/RNA non-specific endonuclease
IPR020821
Extracellular Endonuclease, subunit A
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PFAM |
PF01223
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PRINTS |
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PIRSF |
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SMART |
SM00892
SM00477
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TIGRFAMs |
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Modification |
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SwissProt |
Q9Y2C4
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PhosphoSite |
PhosphoSite-Q9Y2C4
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
9941
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UniGene |
Hs.517897
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RefSeq |
NP_001138936
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HUGO |
HGNC:3347
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OMIM |
604051
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CCDS |
CCDS46795
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HPRD |
06813
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IMGT |
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EMBL |
AB020523
AB020735
AK289602
AK290107
AK301067
AK315814
BC104212
BC104213
CH471055
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GenPept |
AAI04213
AAI04214
BAA76752
BAA76753
BAF82291
BAF82796
BAF98705
BAG62674
EAW64538
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