Version 5.4
Homo sapiens Protein: VARS
Summary
InnateDB Protein IDBP-373047.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol VARS
Protein Name valyl-tRNA synthetase
Synonyms G7A; VARS1; VARS2;
Species Homo sapiens
Ensembl Protein ENSP00000415679
InnateDB Gene IDBG-79175 (VARS)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 42 experimentally validated interaction(s) in this database.
Experimentally validated
Total 42 [view]
Protein-Protein 42 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0006418 tRNA aminoacylation for protein translation
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR002300 Aminoacyl-tRNA synthetase, class Ia
IPR002303 Valine-tRNA ligase
IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding
PFAM PF00133
PRINTS PR00986
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 7407
UniGene Hs.520026
RefSeq
HUGO HGNC:12651
OMIM 192150
CCDS
HPRD 10362
IMGT
EMBL
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca