InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: DHX57

Summary

InnateDB Protein

IDBP-373201.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DHX57

Protein Name

DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000405111

InnateDB Gene

IDBG-47052 (DHX57)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.

Experimentally validated
Total	13 [view]
Protein-Protein	13 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0004386	helicase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008026	ATP-dependent helicase activity
GO:0044822	poly(A) RNA binding
GO:0046872	metal ion binding

Biological Process

GO:0006200

ATP catabolic process

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR000571 Zinc finger, CCCH-type
IPR001650 Helicase, C-terminal
IPR006575 RWD domain
IPR007502 Helicase-associated domain
IPR009060 UBA-like
IPR011545 DEAD/DEAH box helicase domain
IPR011709 Domain of unknown function DUF1605
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR015940 Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote
IPR016135 Ubiquitin-conjugating enzyme/RWD-like
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00642
PF00271
PF05773
PF04408
PF00270
PF07717

PRINTS

PIRSF

SMART

SM00356
SM00490
SM00591
SM00847
SM00487
SM00165

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q6P158