InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: MYO16

Summary

InnateDB Protein

IDBP-373408.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MYO16

Protein Name

myosin XVI

Synonyms

MYAP3; Myo16b; MYR8; NYAP3; PPP1R107;

Species

Homo sapiens

Ensembl Protein

ENSP00000401633

InnateDB Gene

IDBG-49927 (MYO16)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003774	motor activity
GO:0003779	actin binding
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0019903	protein phosphatase binding
GO:0032403	protein complex binding
GO:0051015	actin filament binding

Biological Process

GO:0008152	metabolic process
GO:0008285	negative regulation of cell proliferation
GO:0014065	phosphatidylinositol 3-kinase signaling
GO:0021549	cerebellum development
GO:0048812	neuron projection morphogenesis
GO:2000134	negative regulation of G1/S transition of mitotic cell cycle

Cellular Component

GO:0005654	nucleoplasm
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016459	myosin complex
GO:0048471	perinuclear region of cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR000048 IQ motif, EF-hand binding site
IPR001609 Myosin head, motor domain
IPR002110 Ankyrin repeat
IPR020683 Ankyrin repeat-containing domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00612
PF00063
PF00023
PF13606
PF11929
PF12796

PRINTS

PR00193
PR01415

PIRSF

SMART

SM00015
SM00242
SM00248

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt