Version 5.4
Homo sapiens Protein: PTPMT1
Summary
InnateDB Protein IDBP-373643.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PTPMT1
Protein Name protein tyrosine phosphatase, mitochondrial 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000410272
InnateDB Gene IDBG-43607 (PTPMT1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
GO:0004725 protein tyrosine phosphatase activity
GO:0008138 protein tyrosine/serine/threonine phosphatase activity
GO:0008962 phosphatidylglycerophosphatase activity
Biological Process
GO:0006470 protein dephosphorylation
GO:0006644 phospholipid metabolic process
GO:0006655 phosphatidylglycerol biosynthetic process
GO:0032049 cardiolipin biosynthetic process
GO:0035335 peptidyl-tyrosine dephosphorylation
GO:0044281 small molecule metabolic process
GO:0046474 glycerophospholipid biosynthetic process
GO:0046855 inositol phosphate dephosphorylation
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8WUK0
PhosphoSite PhosphoSite-E9PAT8
TrEMBL
UniProt Splice Variant
Entrez Gene 114971
UniGene Hs.742231
RefSeq NP_001137456
HUGO HGNC:26965
OMIM 609538
CCDS CCDS44593
HPRD
IMGT
EMBL AC090559 AC104942 AF277187 AY333987 BC014048 BC020242 BC073798
GenPept AAH14048 AAH20242 AAK07545 AAP94732

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca