Version 5.4
Homo sapiens Protein: RLN3
Summary
InnateDB Protein IDBP-373867.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RLN3
Protein Name relaxin 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000397415
InnateDB Gene IDBG-32714 (RLN3)
Protein Structure
UniProt Annotation
Function May play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 (GPCR135) and relaxin-3 receptor-2 (GPCR142).
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0001664 G-protein coupled receptor binding
GO:0005179 hormone activity
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR016179 Insulin-like
IPR022352 Insulin family
PFAM PF00049
PRINTS PR00276
PIRSF
SMART SM00078
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8WXF3
PhosphoSite PhosphoSite-Q8WXF3
TrEMBL
UniProt Splice Variant
Entrez Gene 117579
UniGene Hs.352155
RefSeq NP_543140
HUGO HGNC:17135
OMIM 606855
CCDS CCDS12302
HPRD 06031
IMGT
EMBL AB076563 AF447451 AY358181
GenPept AAL40345 AAQ88548 BAC53758

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca