Version 5.4
Homo sapiens Protein: KANSL2
Summary
InnateDB Protein IDBP-373920.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KANSL2
Protein Name chromosome 12 open reading frame 41
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000415436
InnateDB Gene IDBG-30194 (KANSL2)
Protein Structure
UniProt Annotation
Function As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription. {ECO:0000269PubMed:20018852}.
Subcellular Localization Nucleus {ECO:0000269PubMed:20018852}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0043995 histone acetyltransferase activity (H4-K5 specific)
GO:0043996 histone acetyltransferase activity (H4-K8 specific)
GO:0046972 histone acetyltransferase activity (H4-K16 specific)
Biological Process
GO:0006325 chromatin organization
GO:0043981 histone H4-K5 acetylation
GO:0043982 histone H4-K8 acetylation
GO:0043984 histone H4-K16 acetylation
Cellular Component
GO:0000123 histone acetyltransferase complex
GO:0005654 nucleoplasm
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H9L4
PhosphoSite PhosphoSite-Q9H9L4
TrEMBL F8VRX7
UniProt Splice Variant
Entrez Gene 54934
UniGene Hs.505412
RefSeq NP_060292
HUGO HGNC:26024
OMIM 615488
CCDS CCDS44869
HPRD 07907
IMGT
EMBL AC079951 AK000443 AK022732 AL834467 BC009746 BC013900
GenPept AAH09746 AAH13900 BAA91169 BAB14211 CAD39126

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca