Version 5.4
Homo sapiens Protein: ZNF410
Summary
InnateDB Protein IDBP-374102.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF410
Protein Name zinc finger protein 410
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000407130
InnateDB Gene IDBG-11701 (ZNF410)
Protein Structure
UniProt Annotation
Function Transcription factor that activates transcription of matrix-remodeling genes such as MMP1 during fibroblast senescence. {ECO:0000269PubMed:12370286}.
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity Widely expressed. {ECO:0000269PubMed:12370286}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 6 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like
PFAM PF00096
PRINTS
PIRSF
SMART SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q86VK4
PhosphoSite PhosphoSite-Q86VK4
TrEMBL G3V4E6
UniProt Splice Variant
Entrez Gene 57862
UniGene Hs.672523
RefSeq
HUGO HGNC:20144
OMIM
CCDS CCDS55929
HPRD 18339
IMGT
EMBL AC005480 AC005520 AK293350 AK299138 BC000330 BC004357 BC050683 U90919
GenPept AAB51059 AAH50683 BAG56866 BAG61190

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca