Version 5.4
Homo sapiens Protein: AGAP4
Summary
InnateDB Protein IDBP-374123.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AGAP4
Protein Name ArfGAP with GTPase domain, ankyrin repeat and PH domain 4
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000392513
InnateDB Gene IDBG-73323 (AGAP4)
Protein Structure
UniProt Annotation
Function Putative GTPase-activating protein. {ECO:0000305}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008060 ARF GTPase activator activity
GO:0008270 zinc ion binding
Biological Process
GO:0032312 regulation of ARF GTPase activity
GO:0043547 positive regulation of GTPase activity
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001164 Arf GTPase activating protein
IPR001849 Pleckstrin homology domain
IPR002110 Ankyrin repeat
IPR020683 Ankyrin repeat-containing domain
PFAM PF01412
PF00169
PF00023
PF13606
PF11929
PF12796
PRINTS PR00405
PR01415
PIRSF
SMART SM00105
SM00233
SM00248
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96P64
PhosphoSite PhosphoSite-Q96P64
TrEMBL
UniProt Splice Variant
Entrez Gene 729092
UniGene Hs.738876
RefSeq NP_597703
HUGO HGNC:23459
OMIM
CCDS CCDS7215
HPRD 16771
IMGT
EMBL AC012044 AF411132
GenPept AAL10290

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca