InnateDB Protein
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IDBP-374219.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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TMED4
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Protein Name
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transmembrane emp24 protein transport domain containing 4
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000404042
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InnateDB Gene
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IDBG-14997 (TMED4)
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Protein Structure
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Function |
Involved in vesicular protein trafficking, mainly in the early secretory pathway. targeting. Involved in the maintenance of the Golgi apparatus. Appears to play a role in the biosynthesis of secreted cargo including processing. Involved in endoplasmic reticulum stress response. May play a role in the regulation of heat-shock response and apoptosis (By similarity). {ECO:0000250}.
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Subcellular Localization |
Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
10
[view]
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Protein-Protein |
10
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0004871
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signal transducer activity
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR009038
GOLD
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PFAM |
PF01105
PF13897
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q7Z7H5
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PhosphoSite |
PhosphoSite-Q7Z7H5
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
222068
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UniGene |
Hs.598832
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RefSeq |
NP_872353
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HUGO |
HGNC:22301
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OMIM |
612038
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CCDS |
CCDS5493
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HPRD |
13666
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IMGT |
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EMBL |
AB097009
AK074557
AK290125
AK294122
AY191223
BC052641
BC057851
BX647965
CH236960
CH471128
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GenPept |
AAH52641
AAH57851
AAP20105
BAC11058
BAC77362
BAF82814
BAG57455
EAL23751
EAW61090
EAW61091
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