Homo sapiens Protein: SLC25A31
Summary
InnateDB Protein IDBP-37430.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC25A31
Protein Name solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000281154
InnateDB Gene IDBG-37428 (SLC25A31)
Protein Structure
UniProt Annotation
Function Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May serve to mediate energy generating and energy consuming processes in the distal flagellum, possibly as a nucleotide shuttle between flagellar glycolysis, protein phosphorylation and mechanisms of motility. {ECO:0000269PubMed:17137571}.
Subcellular Localization Mitochondrion inner membrane; Multi-pass membrane protein. Cell projection, cilium, flagellum. Note=In sperm flagellum this protein is located in the fibrous sheath, a non-mitochondrial region.
Disease Associations
Tissue Specificity Expressed in brain, liver, sperm and testis. {ECO:0000269PubMed:15670820, ECO:0000269PubMed:17137571}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
Biological Process
GO:0055085 transmembrane transport
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005929 cilium
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR002067 Mitochondrial carrier protein
IPR002113 Adenine nucleotide translocator 1
IPR018108 Mitochondrial substrate/solute carrier
IPR023395 Mitochondrial carrier domain
PFAM PF00153
PRINTS PR00926
PR00927
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H0C2
PhosphoSite PhosphoSite-Q9H0C2
TrEMBL
UniProt Splice Variant
Entrez Gene 83447
UniGene Hs.149030
RefSeq NP_112581
HUGO HGNC:25319
OMIM 610796
CCDS CCDS3733
HPRD 13160
IMGT
EMBL AC093591 AJ863129 AL136857 AY550240 BC022032 CH471056
GenPept AAH22032 AAT42263 AAY40974 CAB66791 CAI05952 EAX05199