Version 5.4
Homo sapiens Protein: ALS2CL
Summary
InnateDB Protein IDBP-374717.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ALS2CL
Protein Name ALS2 C-terminal like
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000405335
InnateDB Gene IDBG-30633 (ALS2CL)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005089 Rho guanyl-nucleotide exchange factor activity
Biological Process
GO:0032321 positive regulation of Rho GTPase activity
GO:0035023 regulation of Rho protein signal transduction
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000219 Dbl homology (DH) domain
IPR003409 MORN motif
PFAM PF00621
PF02493
PRINTS
PIRSF
SMART SM00325
SM00698
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G5E9N5
UniProt Splice Variant
Entrez Gene 259173
UniGene Hs.517937
RefSeq XP_006713155
HUGO HGNC:20605
OMIM 612402
CCDS
HPRD 10643
IMGT
EMBL AC104304 AC134504 CH471055
GenPept EAW64775

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca