InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TNS3

Summary

InnateDB Protein

IDBP-374798.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TNS3

Protein Name

tensin 3

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000414358

InnateDB Gene

IDBG-15881 (TNS3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.

Experimentally validated
Total	17 [view]
Protein-Protein	17 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0016791	phosphatase activity
GO:0046872	metal ion binding

Biological Process

GO:0016311	dephosphorylation
GO:0035556	intracellular signal transduction

Cellular Component

GO:0005737	cytoplasm
GO:0005925	focal adhesion

Protein Structure and Domains

PDB ID

InterPro

IPR000008 C2 domain
IPR000387 Protein-tyrosine/Dual specificity phosphatase
IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
IPR003595 Protein-tyrosine phosphatase, catalytic
IPR014020 Tensin phosphatase, C2 domain
IPR029021 Protein-tyrosine phosphatase-like
IPR029023 Tensin phosphatase, lipid phosphatase domain

PFAM

PF00168
PF00130
PF10409

PRINTS

PR00360

PIRSF

SMART

SM00239
SM00109
SM00404

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt