Homo sapiens Protein: HSPA4L
Summary
InnateDB Protein IDBP-37495.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HSPA4L
Protein Name heat shock 70kDa protein 4-like
Synonyms APG-1; HSPH3; Osp94;
Species Homo sapiens
Ensembl Protein ENSP00000296464
InnateDB Gene IDBG-37493 (HSPA4L)
Protein Structure
UniProt Annotation
Function Possesses chaperone activity in vitro where it inhibits aggregation of citrate synthase. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=May translocate to the nucleus after heat shock. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 34 experimentally validated interaction(s) in this database.
Experimentally validated
Total 34 [view]
Protein-Protein 33 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005524 ATP binding
Biological Process
GO:0000902 cell morphogenesis
GO:0006457 protein folding
GO:0006986 response to unfolded protein
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR004753 Cell shape determining protein MreB/Mrl
IPR013126 Heat shock protein 70 family
IPR029047 Heat shock protein 70kD, peptide-binding domain
IPR029048 Heat shock protein 70kD, C-terminal domain
PFAM PF06723
PF00012
PRINTS PR01652
PR00301
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O95757
PhosphoSite PhosphoSite-O95757
TrEMBL E7ES43
UniProt Splice Variant
Entrez Gene 22824
UniGene Hs.135554
RefSeq NP_055093
HUGO HGNC:17041
OMIM
CCDS CCDS3734
HPRD 07137
IMGT
EMBL AB023421 AC093591 BC040560 CH471056 EF197155
GenPept AAH40560 AAY40975 ABM69040 BAA75063 EAX05198