InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ABCA13

Summary

InnateDB Protein

IDBP-375101.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ABCA13

Protein Name

ATP-binding cassette, sub-family A (ABC1), member 13

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000411096

InnateDB Gene

IDBG-16248 (ABCA13)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Significantly expressed in the bone marrow, trachea, testis, thyroid and lung as well as in skin fibroblasts. {ECO:0000269PubMed:12697998, ECO:0000269PubMed:23266639}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005524	ATP binding
GO:0016887	ATPase activity

Biological Process

GO:0006200	ATP catabolic process
GO:0006810	transport

Cellular Component

GO:0016021

integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR003439 ABC transporter-like
IPR003593 AAA+ ATPase domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00005

PRINTS

PIRSF

SMART

SM00382

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q86UQ4

PhosphoSite

PhosphoSite-Q86UQ4

TrEMBL

UniProt Splice Variant

Entrez Gene

154664

UniGene

Hs.625146

RefSeq

NP_689914

HUGO

HGNC:14638

OMIM

607807

CCDS

CCDS47584

HPRD

07422

IMGT

EMBL

AC073424 AC073927 AC091770 AC095039 AC232300 AC232312 AF501281 AK091270 AK126220 AY204751 JF913488 JF913489 JF913490 JF913491 JF913492

GenPept

AAO59914 AAP13576 AFH89038 AFH89039 AFH89040 AFH89041 AFH89042 BAC03623 BAC86492