InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RPS18

Summary

InnateDB Protein

IDBP-375444.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RPS18

Protein Name

ribosomal protein S18

Synonyms

D6S218E; HKE3; KE-3; KE3; S18;

Species

Homo sapiens

Ensembl Protein

ENSP00000393241

InnateDB Gene

IDBG-304152 (RPS18)

Protein Structure

UniProt Annotation

Function

Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA. {ECO:0000250}.

Subcellular Localization

Cytoplasm.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 104 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	104 [view]
Protein-Protein	103 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0005515	protein binding
GO:0019843	rRNA binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0006412	translation
GO:0006413	translational initiation
GO:0006414	translational elongation
GO:0006415	translational termination
GO:0006614	SRP-dependent cotranslational protein targeting to membrane
GO:0010467	gene expression
GO:0016032	viral process
GO:0016070	RNA metabolic process
GO:0016071	mRNA metabolic process
GO:0019058	viral life cycle
GO:0019083	viral transcription
GO:0042254	ribosome biogenesis
GO:0044267	cellular protein metabolic process

Cellular Component

GO:0005581	collagen trimer
GO:0005622	intracellular
GO:0005634	nucleus
GO:0005829	cytosol
GO:0005840	ribosome
GO:0015935	small ribosomal subunit
GO:0016020	membrane
GO:0022627	cytosolic small ribosomal subunit
GO:0070062	extracellular vesicular exosome