Version 5.4
Homo sapiens Protein: RCAN3
Summary
InnateDB Protein IDBP-375495.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RCAN3
Protein Name RCAN family member 3
Synonyms DSCR1L2; hRCN3; MCIP3; RCN3;
Species Homo sapiens
Ensembl Protein ENSP00000414447
InnateDB Gene IDBG-94221 (RCAN3)
Protein Structure
UniProt Annotation
Function Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity Highest expression in heart, skeletal muscle kidney, liver and peripheral blood leukocytes. Lower expression in all other tissues.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0031013 troponin I binding
Biological Process
GO:0009653 anatomical structure morphogenesis
GO:0019722 calcium-mediated signaling
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR006931 Calcipressin
PFAM PF04847
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UKA8
PhosphoSite PhosphoSite-Q9UKA8
TrEMBL Q5TGC7
UniProt Splice Variant
Entrez Gene 11123
UniGene Hs.741880
RefSeq NP_001238910
HUGO HGNC:3042
OMIM 605860
CCDS CCDS57981
HPRD 05792
IMGT
EMBL AF176116 AF176117 AL034582 AY906854 BC035854 CH471134 EF431960 EF467309 EF529733 HQ287726 HQ317421 HQ317422 HQ317423 HQ317426 HQ317427 HQ317445 HQ317446 JN203053 JN228252
GenPept AAF01684 AAF01685 AAH35854 AAW83514 ABO27184 ABO46010 ABP88933 ADO15700 ADR02808 ADR02809 ADR51177 ADR51178 ADR51179 ADR51182 ADR51183 AEL12453 AEL88283 CAI21916 EAW95133

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca