Version 5.4
Homo sapiens Protein: ALDH7A1
Summary
InnateDB Protein IDBP-375536.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ALDH7A1
Protein Name aldehyde dehydrogenase 7 family, member A1
Synonyms ATQ1; EPD; PDE;
Species Homo sapiens
Ensembl Protein ENSP00000414132
InnateDB Gene IDBG-39345 (ALDH7A1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 28 experimentally validated interaction(s) in this database.
Experimentally validated
Total 28 [view]
Protein-Protein 28 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004029 aldehyde dehydrogenase (NAD) activity
GO:0004043 L-aminoadipate-semialdehyde dehydrogenase activity
GO:0005515 protein binding
GO:0008802 betaine-aldehyde dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
Biological Process
GO:0006081 cellular aldehyde metabolic process
GO:0006554 lysine catabolic process
GO:0007605 sensory perception of sound
GO:0008152 metabolic process
GO:0019285 glycine betaine biosynthetic process from choline
GO:0034641 cellular nitrogen compound metabolic process
GO:0044281 small molecule metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005829 cytosol
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR015590 Aldehyde dehydrogenase domain
IPR016161 Aldehyde/histidinol dehydrogenase
PFAM PF00171
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P49419
PhosphoSite PhosphoSite-P49419
TrEMBL F8VS02
UniProt Splice Variant
Entrez Gene 501
UniGene Hs.685289
RefSeq NP_001189333
HUGO HGNC:877
OMIM 107323
CCDS CCDS56380
HPRD 00124
IMGT
EMBL AC093535 AC099513 AF002696 AK295526 AK297365 AK312459 BC002515 BC071712 BC073174 S74728
GenPept AAB31966 AAC51935 AAH02515 AAH71712 AAH73174 BAG35366 BAG58439 BAG59812

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca