Version 5.4
Homo sapiens Protein: CCDC124
Summary
InnateDB Protein IDBP-375704.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CCDC124
Protein Name coiled-coil domain containing 124
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000408730
InnateDB Gene IDBG-37496 (CCDC124)
Protein Structure
UniProt Annotation
Function Required for proper progression of late cytokinetic stages. {ECO:0000269PubMed:23894443}.
Subcellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269PubMed:23894443}. Midbody {ECO:0000269PubMed:23894443}. Note=Colocalizes with gamma-tubulin at interphase, prophase, metaphase, and anaphase. Relocates from centrosome to midbody at telophase.
Disease Associations
Tissue Specificity Ubiquitously expressed. {ECO:0000269PubMed:23894443}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0044822 poly(A) RNA binding
Biological Process
GO:0007049 cell cycle
GO:0051301 cell division
Cellular Component
GO:0005737 cytoplasm
GO:0005815 microtubule organizing center
GO:0005886 plasma membrane
GO:0030496 midbody
Protein Structure and Domains
PDB ID
InterPro IPR009071 High mobility group box domain
IPR010422 Protein of unknown function DUF1014
PFAM PF00505
PF09011
PF06244
PRINTS
PIRSF
SMART SM00398
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96CT7
PhosphoSite PhosphoSite-Q96CT7
TrEMBL M0R2F5
UniProt Splice Variant
Entrez Gene 115098
UniGene
RefSeq NP_001129675
HUGO HGNC:25171
OMIM
CCDS CCDS12369
HPRD 14008
IMGT
EMBL AC005602 AC011540 BC013949 CH471106
GenPept AAH13949 EAW84644 EAW84645

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca