InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PCBP2

Summary

InnateDB Protein

IDBP-376399.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PCBP2

Protein Name

poly(rC) binding protein 2

Synonyms

hnRNP-E2; HNRNPE2; HNRPE2;

Species

Homo sapiens

Ensembl Protein

ENSP00000390304

InnateDB Gene

IDBG-36771 (PCBP2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 83 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	83 [view]
Protein-Protein	80 [view]
Protein-DNA	0
Protein-RNA	3 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0019899	enzyme binding
GO:0031625	ubiquitin protein ligase binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000398	mRNA splicing, via spliceosome
GO:0008380	RNA splicing
GO:0010467	gene expression
GO:0016071	mRNA metabolic process
GO:0032480	negative regulation of type I interferon production
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045087	innate immune response (InnateDB)
GO:0050687	negative regulation of defense response to virus
GO:0051607	defense response to virus

Cellular Component

GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0016020	membrane
GO:0030529	ribonucleoprotein complex
GO:0070062	extracellular vesicular exosome