InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NARS

Summary

InnateDB Protein

IDBP-3765.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NARS

Protein Name

asparaginyl-tRNA synthetase

Synonyms

ASNRS; NARS1;

Species

Homo sapiens

Ensembl Protein

ENSP00000256854

InnateDB Gene

IDBG-3763 (NARS)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Cytoplasm.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 35 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	35 [view]
Protein-Protein	35 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0004812	aminoacyl-tRNA ligase activity
GO:0004816	asparagine-tRNA ligase activity
GO:0005524	ATP binding

Biological Process

GO:0006418	tRNA aminoacylation for protein translation
GO:0006421	asparaginyl-tRNA aminoacylation
GO:0010467	gene expression

Cellular Component

GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005829	cytosol
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb
IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N)
IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type
IPR004522 Asparagine-tRNA ligase
IPR006195 Aminoacyl-tRNA synthetase, class II
IPR012340 Nucleic acid-binding, OB-fold

PFAM

PF00152
PF01336

PRINTS

PR01042

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O43776