Version 5.4
Homo sapiens Protein: GAGE1
Summary
InnateDB Protein IDBP-37698.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GAGE1
Protein Name G antigen 1
Synonyms CT4.1; GAGE-1;
Species Homo sapiens
Ensembl Protein ENSP00000371128
InnateDB Gene IDBG-37650 (GAGE1)
Protein Structure
UniProt Annotation
Function Antigen, recognized on melanoma by autologous cytolytic T-lymphocytes. Completely silent in normal adult tissues, except testis.
Subcellular Localization
Disease Associations
Tissue Specificity Expressed in a variety of tumor tissues but not in normal tissues, except testis.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006968 cellular defense response
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR008625 GAGE
PFAM PF05831
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q13065
PhosphoSite PhosphoSite-Q13065
TrEMBL
UniProt Splice Variant
Entrez Gene 729442
UniGene Hs.278606
RefSeq
HUGO HGNC:4098
OMIM 300735
CCDS
HPRD 05028
IMGT
EMBL AC142496 AC142497 U19142
GenPept AAA82744

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca