InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: FGR

Summary

InnateDB Protein

IDBP-377057.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FGR

Protein Name

Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog

Synonyms

c-fgr; c-src2; p55-Fgr; p55c-fgr; p58-Fgr; p58c-fgr; SRC2;

Species

Homo sapiens

Ensembl Protein

ENSP00000407670

InnateDB Gene

IDBG-94937 (FGR)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 31 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	31 [view]
Protein-Protein	31 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0006468	protein phosphorylation
GO:0045087	innate immune response

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR000719 Protein kinase domain
IPR000980 SH2 domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR001452 SH3 domain
IPR011009 Protein kinase-like domain
IPR011511 Variant SH3 domain

PFAM