Version 5.4
Homo sapiens Protein: PDGFB
Summary
InnateDB Protein IDBP-377122.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PDGFB
Protein Name platelet-derived growth factor beta polypeptide
Synonyms c-sis; IBGC5; PDGF-2; PDGF2; SIS; SSV;
Species Homo sapiens
Ensembl Protein ENSP00000405780
InnateDB Gene IDBG-8091 (PDGFB)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 36 experimentally validated interaction(s) in this database.
Experimentally validated
Total 36 [view]
Protein-Protein 36 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008083 growth factor activity
Biological Process
GO:0051781 positive regulation of cell division
Cellular Component
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR000072 PDGF/VEGF domain
IPR006782 Platelet-derived growth factor, N-terminal
IPR029034 Cystine-knot cytokine
PFAM PF00341
PF04692
PRINTS
PIRSF
SMART SM00141
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q9UE57
UniProt Splice Variant
Entrez Gene 5155
UniGene Hs.1976
RefSeq
HUGO HGNC:8800
OMIM 190040
CCDS
HPRD 01815
IMGT
EMBL X00560 Z81010
GenPept CAA25227

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca