Homo sapiens Protein: PPP2R5C
Summary
InnateDB Protein IDBP-377622.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPP2R5C
Protein Name protein phosphatase 2, regulatory subunit B', gamma
Synonyms B56G; PR61G;
Species Homo sapiens
Ensembl Protein ENSP00000412324
InnateDB Gene IDBG-20535 (PPP2R5C)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 44 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 44 [view]
Protein-Protein 44 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
GO:0008601 protein phosphatase type 2A regulator activity
Biological Process
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0007165 signal transduction
GO:0008285 negative regulation of cell proliferation
GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0050790 regulation of catalytic activity
Cellular Component
GO:0000159 protein phosphatase type 2A complex
GO:0000775 chromosome, centromeric region
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR002554 Protein phosphatase 2A, regulatory B subunit, B56
IPR016024 Armadillo-type fold
PFAM PF01603
PRINTS
PIRSF PIRSF028043
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q13362
PhosphoSite PhosphoSite-Q13362
TrEMBL H0YJ75
UniProt Splice Variant
Entrez Gene 5527
UniGene Hs.733086
RefSeq NP_001155197
HUGO HGNC:9311
OMIM 601645
CCDS CCDS53912
HPRD 03385
IMGT
EMBL AB451341 AK131391 AK302470 AL118558 AL137779 CH471061 D26445 L42375 U37352 Z69030
GenPept AAC37603 AAC50387 BAA05465 BAD18542 BAG63760 BAG70155 CAA93154 EAW81756