Version 5.4
Homo sapiens Protein: TBC1D9
Summary
InnateDB Protein IDBP-377977.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TBC1D9
Protein Name TBC1 domain family, member 9 (with GRAM domain)
Synonyms MDR1;
Species Homo sapiens
Ensembl Protein ENSP00000411197
InnateDB Gene IDBG-38891 (TBC1D9)
Protein Structure
UniProt Annotation
Function May act as a GTPase-activating protein for Rab family protein(s).
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005097 Rab GTPase activator activity
GO:0005509 calcium ion binding
Biological Process
GO:0032313 regulation of Rab GTPase activity
GO:0032851 positive regulation of Rab GTPase activity
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000195 Rab-GTPase-TBC domain
IPR002048 EF-hand domain
IPR004182 GRAM domain
PFAM PF00566
PF00036
PF13202
PF13405
PF02893
PRINTS
PIRSF
SMART SM00164
SM00054
SM00568
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6ZT07
PhosphoSite PhosphoSite-Q6ZT07
TrEMBL
UniProt Splice Variant
Entrez Gene 23158
UniGene Hs.595450
RefSeq NP_055945
HUGO HGNC:21710
OMIM
CCDS CCDS47136
HPRD 11115
IMGT
EMBL AB020689 AB449892 AK127020 BC146758 CH471056
GenPept AAI46759 BAA74905 BAC86789 BAH16635 EAX05092 EAX05094

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca