InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PTGES3

Summary

InnateDB Protein

IDBP-378185.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PTGES3

Protein Name

prostaglandin E synthase 3 (cytosolic)

Synonyms

cPGES; P23; TEBP;

Species

Homo sapiens

Ensembl Protein

ENSP00000402385

InnateDB Gene

IDBG-41485 (PTGES3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 97 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	97 [view]
Protein-Protein	93 [view]
Protein-DNA	4 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003720	telomerase activity
GO:0005515	protein binding
GO:0050220	prostaglandin-E synthase activity
GO:0051082	unfolded protein binding

Biological Process

GO:0000723	telomere maintenance
GO:0001516	prostaglandin biosynthetic process
GO:0006278	RNA-dependent DNA replication
GO:0007165	signal transduction
GO:0019369	arachidonic acid metabolic process
GO:0019371	cyclooxygenase pathway
GO:0044281	small molecule metabolic process
GO:0070389	chaperone cofactor-dependent protein refolding

Cellular Component

GO:0000781	chromosome, telomeric region
GO:0005634	nucleus
GO:0005697	telomerase holoenzyme complex
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0070062	extracellular vesicular exosome