Homo sapiens Protein: ORM2
Summary
InnateDB Protein IDBP-378461.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ORM2
Protein Name orosomucoid 2
Synonyms AGP-B; AGP-B\'; AGP2;
Species Homo sapiens
Ensembl Protein ENSP00000394936
InnateDB Gene IDBG-305538 (ORM2)
Protein Structure
UniProt Annotation
Function Functions as transport protein in the blood stream. Binds various hydrophobic ligands in the interior of its beta- barrel domain. Also binds synthetic drugs and influences their distribution and availability. Appears to function in modulating the activity of the immune system during the acute-phase reaction. {ECO:0000269PubMed:21349832}.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity Expressed by the liver and secreted in plasma.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0002682 regulation of immune system process
GO:0006810 transport
GO:0006953 acute-phase response
Cellular Component
GO:0005615 extracellular space
GO:0072562 blood microparticle
Protein Structure and Domains
PDB ID
InterPro IPR000566 Lipocalin/cytosolic fatty-acid binding domain
IPR001500 Alpha-1-acid glycoprotein
IPR011038 Calycin-like
IPR022734 Apolipoprotein M
PFAM PF00061
PF08212
PF11032
PRINTS PR00708
PIRSF PIRSF036899
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P19652
PhosphoSite PhosphoSite-P19652
TrEMBL
UniProt Splice Variant
Entrez Gene 5005
UniGene
RefSeq NP_000599
HUGO HGNC:8499
OMIM 138610
CCDS CCDS6804
HPRD 00725
IMGT
EMBL AK312226 AL356796 BC015964 BC056239 CH471090 CR456930 M21540 X05780 X05784 X06674 X06675 X06676 X06677 X06678 X06679 X06680
GenPept AAA51549 AAH15964 AAH56239 BAG35159 CAA29873 CAA29874 CAG33211 CAI16860 EAW87417