Homo sapiens Protein: COMMD5
Summary
InnateDB Protein IDBP-378572.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol COMMD5
Protein Name COMM domain containing 5
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000394331
InnateDB Gene IDBG-41735 (COMMD5)
Protein Structure
UniProt Annotation
Function Down-regulates activation of NF-kappa-B. {ECO:0000269PubMed:15799966}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity Highly expressed in heart, stomach, jejunum, kidney, liver, and adrenal gland. Expression was generally higher in adult organs than in fetal tissues, particularly in heart, kidney, and liver. {ECO:0000269PubMed:10918053, ECO:0000269PubMed:15799966}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR009886 HCaRG
PFAM PF07258
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9GZQ3
PhosphoSite PhosphoSite-Q9GZQ3
TrEMBL E9PJE4
UniProt Splice Variant
Entrez Gene 28991
UniGene Hs.690392
RefSeq NP_001074472
HUGO HGNC:17902
OMIM 608216
CCDS CCDS6436
HPRD 16301
IMGT
EMBL AF113540 AF235103 AF290195 AK001477 AK023070 BC002672 BC003055 BC065729 CH471162
GenPept AAF14877 AAG09915 AAH02672 AAH03055 AAH65729 BAA91714 BAB14389 EAW82033 EAW82034 EAW82035 EAW82036 EAW82037