Homo sapiens Protein: HARS
Summary
InnateDB Protein IDBP-378664.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HARS
Protein Name histidyl-tRNA synthetase
Synonyms HRS; USH3B;
Species Homo sapiens
Ensembl Protein ENSP00000411085
InnateDB Gene IDBG-49355 (HARS)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 34 experimentally validated interaction(s) in this database.
Experimentally validated
Total 34 [view]
Protein-Protein 32 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004812 aminoacyl-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0006418 tRNA aminoacylation for protein translation
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR000738 WHEP-TRS
IPR004154 Anticodon-binding
IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit
IPR009068 S15/NS1, RNA-binding
PFAM PF00458
PF03129
PRINTS
PIRSF PIRSF001549
SMART SM00991
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D6RF05
UniProt Splice Variant
Entrez Gene 3035
UniGene Hs.595156
RefSeq NP_001276021
HUGO HGNC:4816
OMIM 142810
CCDS CCDS75324
HPRD 00827
IMGT
EMBL AC116353 AK293154
GenPept BAG56699