InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ATP6V1B1

Summary

InnateDB Protein

IDBP-378841.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ATP6V1B1

Protein Name

ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1

Synonyms

ATP6B1; RTA1B; VATB; VMA2; VPP3;

Species

Homo sapiens

Ensembl Protein

ENSP00000388353

InnateDB Gene

IDBG-55733 (ATP6V1B1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 88 experimentally validated interaction(s) in this database.

Experimentally validated
Total	88 [view]
Protein-Protein	88 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005524	ATP binding
GO:0016820	hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances

Biological Process

GO:0015991	ATP hydrolysis coupled proton transport
GO:0015992	proton transport
GO:0046034	ATP metabolic process

Cellular Component

GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain
GO:0033180	proton-transporting V-type ATPase, V1 domain

Protein Structure and Domains

PDB ID

InterPro

IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain
IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal
IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain
IPR005723 ATPase, V1 complex, subunit B
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00006
PF00306
PF02874

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-