Version 5.4
Homo sapiens Protein: ABHD14B
Summary
InnateDB Protein IDBP-37937.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ABHD14B
Protein Name abhydrolase domain containing 14B
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000354841
InnateDB Gene IDBG-37935 (ABHD14B)
Protein Structure
UniProt Annotation
Function Has hydrolase activity towards p-nitrophenyl butyrate (in vitro). May activate transcription. {ECO:0000269PubMed:14672934}.
Subcellular Localization Cytoplasm. Nucleus. Note=Predominantly cytoplasmic.
Disease Associations
Tissue Specificity Ubiquitous. Detected in spleen, thymus, prostate, testis, ovary, small intestine, colon, peripheral blood leukocyte, heart, placenta, lung, liver, skeletal muscle, pancreas and kidney. {ECO:0000269PubMed:14672934}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0016787 hydrolase activity
Biological Process
GO:0008152 metabolic process
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR029058 Alpha/Beta hydrolase fold
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96IU4
PhosphoSite PhosphoSite-Q96IU4
TrEMBL V9HW87
UniProt Splice Variant
Entrez Gene 84836
UniGene
RefSeq NP_001139786
HUGO HGNC:28235
OMIM
CCDS CCDS2842
HPRD 17504
IMGT
EMBL AK075034 AK075112 AK096073 BC007234 BC050650 BC056411 CH471055 FJ224306
GenPept AAH07234 AAH50650 AAH56411 ACI45998 BAC04696 BAC11366 BAC11408 EAW65178 EAW65179

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca