Version 5.4
Homo sapiens Protein: RUNDC3A
Summary
InnateDB Protein IDBP-379565.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RUNDC3A
Protein Name RUN domain containing 3A
Synonyms RAP2IP; RPIP-8; RPIP8;
Species Homo sapiens
Ensembl Protein ENSP00000410862
InnateDB Gene IDBG-53683 (RUNDC3A)
Protein Structure
UniProt Annotation
Function May act as an effector of RAP2A in neuronal cells. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005083 small GTPase regulator activity
GO:0030250 guanylate cyclase activator activity
GO:0051428 peptide hormone receptor binding
Biological Process
GO:0007264 small GTPase mediated signal transduction
GO:0030828 positive regulation of cGMP biosynthetic process
GO:0031284 positive regulation of guanylate cyclase activity
Cellular Component
GO:0005829 cytosol
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID
InterPro IPR004012 RUN
PFAM PF02759
PRINTS
PIRSF
SMART SM00593
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q59EK9
PhosphoSite PhosphoSite-Q59EK9
TrEMBL
UniProt Splice Variant
Entrez Gene 10900
UniGene Hs.613977
RefSeq NP_001138297
HUGO HGNC:16984
OMIM 605448
CCDS CCDS45698
HPRD 16106
IMGT
EMBL AB209802 AF055026 AK313669 AL133657 BC006194 BX537443 CH471178 CR456748 U93871
GenPept AAB68767 AAC09366 AAH06194 BAD93039 BAG36421 CAB63771 CAD97685 CAG33029 EAW51609 EAW51610

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca