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InnateDB Protein
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IDBP-380264.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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GRAMD4
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Protein Name
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GRAM domain containing 4
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Synonyms
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dA59H18.1; DIP; dJ439F8.1;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000409784
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InnateDB Gene
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IDBG-12191 (GRAMD4)
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Protein Structure
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| Function |
Plays a role as a mediator of E2F1-induced apoptosis in the absence of p53/TP53. {ECO:0000269PubMed:15565177}.
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| Subcellular Localization |
Mitochondrion membrane {ECO:0000305}; Multi- pass membrane protein {ECO:0000305}. Note=Colocalizes with COX4I1. {ECO:0000269PubMed:15565177}.
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| Disease Associations |
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| Tissue Specificity |
Expressed in lung and in primary lung squamous cell carcinoma (LSCC). {ECO:0000269PubMed:18302964}.
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
| Experimentally validated |
| Total |
3
[view]
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| Protein-Protein |
3
[view]
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| Protein-DNA |
0
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| Protein-RNA |
0
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| DNA-DNA |
0
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| RNA-RNA |
0
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| DNA-RNA |
0
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| PDB ID |
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| InterPro |
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| PFAM |
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| PRINTS |
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| PIRSF |
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| SMART |
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| TIGRFAMs |
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| Modification |
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| SwissProt |
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| PhosphoSite |
PhosphoSite-Q6IC98
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| TrEMBL |
X6RIP6
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| UniProt Splice Variant |
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| Entrez Gene |
23151
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| UniGene |
Hs.475150
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| RefSeq |
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| HUGO |
HGNC:29113
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| OMIM |
613691
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| CCDS |
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| HPRD |
11107
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| IMGT |
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| EMBL |
AL021392
AL096766
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| GenPept |
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Version 5.4