InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SLMAP

Summary

InnateDB Protein

IDBP-380381.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLMAP

Protein Name

sarcolemma associated protein

Synonyms

SLAP;

Species

Homo sapiens

Ensembl Protein

ENSP00000398661

InnateDB Gene

IDBG-41431 (SLMAP)

Protein Structure

UniProt Annotation

Function

May play a role during myoblast fusion. {ECO:0000250}.

Subcellular Localization

Cell membrane, sarcolemma {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Note=Membrane-associated. Distributed in the transverse tubules and near the junctional sarcoplasmic reticulum. Detected along the Z- and M-lines in cardiomyocytes. Centrosome. Localizes to the centrosomes in a microtubule- dependent manner (By similarity). {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 60 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	60 [view]
Protein-Protein	60 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0051082	unfolded protein binding

Biological Process

GO:0006457	protein folding
GO:0006936	muscle contraction

Cellular Component

GO:0005790	smooth endoplasmic reticulum
GO:0005815	microtubule organizing center
GO:0005887	integral component of plasma membrane
GO:0016272	prefoldin complex
GO:0042383	sarcolemma