Polyglutamylase which preferentially modifies alpha- tubulin. Mediates tubulin polyglutamylation in cilia. Involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step (By similarity). {ECO:0000250}.
Subcellular Localization
Cell projection, cilium {ECO:0000269PubMed:22246503}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269PubMed:22246503}. Note=CEP41 is required for its transport between the basal body and the cilium.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions
This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.