InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RALGPS1

Summary

InnateDB Protein

IDBP-380610.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RALGPS1

Protein Name

Ral GEF with PH domain and SH3 binding motif 1

Synonyms

RALGEF2; RALGPS1A;

Species

Homo sapiens

Ensembl Protein

ENSP00000415630

InnateDB Gene

IDBG-85534 (RALGPS1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005085	guanyl-nucleotide exchange factor activity
GO:0008321	Ral guanyl-nucleotide exchange factor activity

Biological Process

GO:0007264	small GTPase mediated signal transduction
GO:0032485	regulation of Ral protein signal transduction
GO:0032852	positive regulation of Ral GTPase activity
GO:0035556	intracellular signal transduction
GO:0043547	positive regulation of GTPase activity

Cellular Component

GO:0005575	cellular_component
GO:0005737	cytoplasm
GO:0005886	plasma membrane

Protein Structure and Domains

PDB ID

InterPro

IPR001849 Pleckstrin homology domain
IPR001895 Ras guanine-nucleotide exchange factors catalytic domain
IPR023578 Ras guanine nucleotide exchange factor domain

PFAM

PF00169
PF00617

PRINTS

PIRSF

SMART

SM00233
SM00147

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q5JS13