Homo sapiens Protein: PGPEP1
Summary
InnateDB Protein IDBP-38065.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PGPEP1
Protein Name pyroglutamyl-peptidase I
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000269919
InnateDB Gene IDBG-38042 (PGPEP1)
Protein Structure
UniProt Annotation
Function Removes 5-oxoproline from various penultimate amino acid residues except L-proline. {ECO:0000269PubMed:12651114}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008234 cysteine-type peptidase activity
GO:0016920 pyroglutamyl-peptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR000816 Peptidase C15, pyroglutamyl peptidase I
IPR016125 Peptidase C15, pyroglutamyl peptidase I-like
PFAM PF01470
PRINTS PR00706
PIRSF PIRSF015592
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NXJ5
PhosphoSite PhosphoSite-Q9NXJ5
TrEMBL U3KQG9
UniProt Splice Variant
Entrez Gene 54858
UniGene Hs.131776
RefSeq NP_060182
HUGO HGNC:13568
OMIM 610694
CCDS CCDS12375
HPRD 07141
IMGT
EMBL AC008397 AJ278828 AK000215 AK289968 AK294497 BC042138 CH471106
GenPept AAH42138 BAA91015 BAF82657 BAG57716 CAC03610 EAW84691 EAW84692