InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TRIM54

Summary

InnateDB Protein

IDBP-38093.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TRIM54

Protein Name

tripartite motif containing 54

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000296098

InnateDB Gene

IDBG-38087 (TRIM54)

Protein Structure

UniProt Annotation

Function

May bind and stabilize microtubules during myotubes formation. {ECO:0000250}.

Subcellular Localization

Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250}. Note=Associates with microtubules. Localizes to the Z-lines in skeletal muscles (By similarity). {ECO:0000250}.

Disease Associations

Tissue Specificity

Specifically expressed in heart and skeletal muscle. {ECO:0000269PubMed:11243782}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 33 experimentally validated interaction(s) in this database.

Experimentally validated
Total	33 [view]
Protein-Protein	33 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004871	signal transducer activity
GO:0005515	protein binding
GO:0008017	microtubule binding
GO:0008270	zinc ion binding
GO:0046872	metal ion binding

Biological Process

GO:0007017	microtubule-based process
GO:0007026	negative regulation of microtubule depolymerization
GO:0007165	signal transduction
GO:0007275	multicellular organismal development
GO:0030154	cell differentiation
GO:0046417	chorismate metabolic process