Version 5.4
Homo sapiens Protein: HSDL1
Summary
InnateDB Protein IDBP-381277.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HSDL1
Protein Name hydroxysteroid dehydrogenase like 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000407437
InnateDB Gene IDBG-44236 (HSDL1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Mitochondrion {ECO:0000269PubMed:19026618}.
Disease Associations
Tissue Specificity Highly expressed in testis and ovary. Also detected in thyroid, spinal cord, adrenal gland, heart, placenta, skeletal muscle, small intestine, colon, spleen, prostate and pancreas. {ECO:0000269PubMed:12153137, ECO:0000269PubMed:19026618}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016491 oxidoreductase activity
Biological Process
GO:0008152 metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID
InterPro IPR002198 Short-chain dehydrogenase/reductase SDR
IPR002347 Glucose/ribitol dehydrogenase
PFAM PF00106
PRINTS PR00080
PR00081
PIRSF PIRSF000126
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3SXM5
PhosphoSite PhosphoSite-Q3SXM5
TrEMBL H3BNH5
UniProt Splice Variant
Entrez Gene 83693
UniGene Hs.641987
RefSeq NP_001139523
HUGO HGNC:16475
OMIM
CCDS CCDS54046
HPRD 17117
IMGT
EMBL AC040169 AF237684 AK074878 AK299798 AY028377 BC104218 BC104219 BC106917 CH471114
GenPept AAI04219 AAI04220 AAI06918 AAK15047 AAK16927 BAC11262 BAG61674 EAW95502 EAW95503 EAW95504

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca