InnateDB Protein
|
IDBP-381333.4
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
NCAPH2
|
Protein Name
|
non-SMC condensin II complex, subunit H2
|
Synonyms
|
|
Species
|
Homo sapiens
|
Ensembl Protein
|
ENSP00000410088
|
InnateDB Gene
|
IDBG-13668 (NCAPH2)
|
Protein Structure
|
|
Function |
Regulatory subunit of the condensin-2 complex, a complex that seems to provide chromosomes with an additional level of organization and rigidity and in establishing mitotic chromosome architecture. May play a role in lineage-specific role in T-cell development (By similarity). {ECO:0000250}.
|
Subcellular Localization |
Nucleus {ECO:0000269PubMed:14532007}. Chromosome {ECO:0000269PubMed:14532007}. Note=Distributed along the arms of chromosomes assembled in vivo and in vitro.
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
16
[view]
|
Protein-Protein |
15
[view]
|
Protein-DNA |
1
[view]
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
Predicted by orthology |
Total |
1 [view]
|
|
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
|
InterPro |
IPR009378
Non-SMC condensin II complex, subunit H2-like
|
PFAM |
PF06278
|
PRINTS |
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q6IBW4
|
PhosphoSite |
PhosphoSite-Q6IBW4
|
TrEMBL |
|
UniProt Splice Variant |
|
Entrez Gene |
29781
|
UniGene |
Hs.730607
|
RefSeq |
NP_689512
|
HUGO |
HGNC:25071
|
OMIM |
611230
|
CCDS |
CCDS14094
|
HPRD |
|
IMGT |
|
EMBL |
AL021682
BC000473
BC001509
BC001833
BC001937
BC009441
BC014939
CH471138
CR456604
U62317
|
GenPept |
AAB03345
AAH00473
AAH01509
AAH01833
AAH01937
AAH09441
AAH14939
CAA16670
CAG30490
EAW73552
EAW73554
EAW73556
|
|
|