Version 5.4
Homo sapiens Protein: TSPAN14
Summary
InnateDB Protein IDBP-381489.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TSPAN14
Protein Name tetraspanin 14
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000396270
InnateDB Gene IDBG-80531 (TSPAN14)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 4 [view]
Protein-DNA 1 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0019899 enzyme binding
Biological Process
GO:0045747 positive regulation of Notch signaling pathway
GO:0051604 protein maturation
GO:0090002 establishment of protein localization to plasma membrane
Cellular Component
GO:0005886 plasma membrane
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0097197 tetraspanin-enriched microdomain
Protein Structure and Domains
PDB ID
InterPro IPR000301 Tetraspanin
IPR008952 Tetraspanin, EC2 domain
IPR018499 Tetraspanin/Peripherin
PFAM PF00335
PRINTS PR00259
PIRSF PIRSF002419
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8NG11
PhosphoSite PhosphoSite-Q8NG11
TrEMBL
UniProt Splice Variant
Entrez Gene 81619
UniGene Hs.736780
RefSeq NP_112189
HUGO HGNC:23303
OMIM
CCDS CCDS7369
HPRD 18196
IMGT
EMBL AC021028 AF311903 AK295321 AL136638 BC002920 BC093016 CH471142
GenPept AAH02920 AAH93016 AAM94899 BAG58298 CAB66573 EAW80384 EAW80385 EAW80386 EAW80388 EAW80389

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca