InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RIMKLA

Summary

InnateDB Protein

IDBP-381621.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RIMKLA

Protein Name

ribosomal modification protein rimK-like family member A

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000414330

InnateDB Gene

IDBG-97197 (RIMKLA)

Protein Structure

UniProt Annotation

Function

Catalyzes the synthesis of N-acetyl-L-aspartyl-L- glutamate (NAAG) and N-acetyl-L-aspartyl-L-glutamyl-L-glutamate.

Subcellular Localization

Cytoplasm {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004363	glutathione synthase activity
GO:0005524	ATP binding
GO:0046872	metal ion binding
GO:0072590	N-acetyl-L-aspartate-L-glutamate ligase activity

Biological Process

GO:0006464	cellular protein modification process
GO:0006750	glutathione biosynthetic process
GO:0008152	metabolic process

Cellular Component

GO:0005737

cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR003806 ATP-grasp fold, DUF201-type
IPR004218 Prokaryotic glutathione synthetase, ATP-binding
IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX
IPR011761 ATP-grasp fold
IPR013651 ATP-grasp fold, RimK-type

PFAM

PF02655
PF02955
PF08443

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8IXN7

PhosphoSite