Homo sapiens Protein: KDM4E
Summary
InnateDB Protein IDBP-382273.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KDM4E
Protein Name lysine (K)-specific demethylase 4D-like
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000397239
InnateDB Gene IDBG-307137 (KDM4E)
Protein Structure
UniProt Annotation
Function Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a central role in histone code. {ECO:0000269PubMed:21914792}.
Subcellular Localization Nucleus {ECO:0000255PROSITE- ProRule:PRU00537}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0016568 chromatin modification
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR003347 JmjC domain
IPR003349 Transcription factor jumonji, JmjN
PFAM PF02373
PF08007
PF02375
PRINTS
PIRSF
SMART SM00558
SM00545
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt B2RXH2
PhosphoSite PhosphoSite-B2RXH2
TrEMBL
UniProt Splice Variant
Entrez Gene 390245
UniGene Hs.714692
RefSeq NP_001155102
HUGO HGNC:37098
OMIM
CCDS CCDS44713
HPRD
IMGT
EMBL AP002383 BC157851 BC157889 BC171916
GenPept AAI57852 AAI57890 AAI71916