Version 5.4
| Homo sapiens Protein: TMPRSS7 | |||||||||||
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| Summary | |||||||||||
| InnateDB Protein | IDBP-382383.5 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | TMPRSS7 | ||||||||||
| Protein Name | transmembrane protease, serine 7 | ||||||||||
| Synonyms | |||||||||||
| Species | Homo sapiens | ||||||||||
| Ensembl Protein | ENSP00000398236 | ||||||||||
| InnateDB Gene | IDBG-49692 (TMPRSS7) | ||||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||||
| Function | Serine protease which preferentially hydrolyzes peptides with Arg at the P1 position. {ECO:0000250}. | ||||||||||
| Subcellular Localization | Cell membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. | ||||||||||
| Disease Associations | |||||||||||
| Tissue Specificity | Expressed in brain, ovary, testis, salivary gland, trachea and lung. {ECO:0000269PubMed:15853774}. | ||||||||||
| Comments | |||||||||||
| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||||
| PDB ID | |||||||||||
| InterPro |
IPR000082
SEA domain IPR000859 CUB domain IPR001254 Peptidase S1 IPR001314 Peptidase S1A, chymotrypsin-type IPR002172 Low-density lipoprotein (LDL) receptor class A repeat IPR009003 Trypsin-like cysteine/serine peptidase domain |
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| PFAM |
PF01390
PF00431 PF00089 PF00057 |
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| PRINTS |
PR00722
PR00261 |
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| PIRSF | |||||||||||
| SMART |
SM00200
SM00042 SM00020 SM00192 |
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| TIGRFAMs | |||||||||||
| Post-translational Modifications | |||||||||||
| Modification | |||||||||||
| Cross-References | |||||||||||
| SwissProt | Q7RTY8 | ||||||||||
| PhosphoSite | PhosphoSite-Q7RTY8 | ||||||||||
| TrEMBL | |||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | 344805 | ||||||||||
| UniGene | Hs.435490 | ||||||||||
| RefSeq | |||||||||||
| HUGO | HGNC:30846 | ||||||||||
| OMIM | |||||||||||
| CCDS | |||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| EMBL | AC015778 AC024887 AK131211 BC117322 BN000125 | ||||||||||
| GenPept | AAI17323 BAD18401 CAD67577 | ||||||||||