InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PWP1

Summary

InnateDB Protein

IDBP-382579.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PWP1

Protein Name

PWP1 homolog (S. cerevisiae)

Synonyms

IEF-SSP-9502;

Species

Homo sapiens

Ensembl Protein

ENSP00000387365

InnateDB Gene

IDBG-55140 (PWP1)

Protein Structure

UniProt Annotation

Function

May play an important role in cell growth and/or transcription.

Subcellular Localization

Nucleus.

Disease Associations

Tissue Specificity

High levels seen in the placenta, skeletal muscle, kidney and pancreas while lower levels were seen in the heart, brain and lung.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	25 [view]
Protein-Protein	24 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0006351

transcription, DNA-templated

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005794	Golgi apparatus

Protein Structure and Domains

PDB ID

InterPro

IPR001680 WD40 repeat
IPR017986 WD40-repeat-containing domain
IPR020472 G-protein beta WD-40 repeat

PFAM

PF00400

PRINTS

PR00320

PIRSF

SMART

SM00320

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q13610

PhosphoSite

PhosphoSite-Q13610

TrEMBL

Q86X79

UniProt Splice Variant

Entrez Gene

11137

UniGene

Hs.506652

RefSeq

NP_008993

HUGO

HGNC:17015

OMIM

CCDS

CCDS9114

HPRD

11464

IMGT

EMBL

AC007622 AK290681 AK296252 BC040135 BC046144 CH471054 L07758

GenPept

AAA65201 AAH40135 AAH46144 BAF83370 BAG58967 EAW97802 EAW97803