InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TCF15

Summary

InnateDB Protein

IDBP-38259.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TCF15

Protein Name

transcription factor 15 (basic helix-loop-helix)

Synonyms

bHLHa40; EC2; PARAXIS;

Species

Homo sapiens

Ensembl Protein

ENSP00000246080

InnateDB Gene

IDBG-38257 (TCF15)

Protein Structure

UniProt Annotation

Function

May function as an early transcriptional regulator, involved in the patterning of the mesoderm and in lineage determination of cell types derived from the mesoderm.

Subcellular Localization

Nucleus {ECO:0000255PROSITE- ProRule:PRU00981}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0046983	protein dimerization activity

Biological Process

GO:0001756	somitogenesis
GO:0003016	respiratory system process
GO:0006351	transcription, DNA-templated
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0007498	mesoderm development
GO:0007517	muscle organ development
GO:0009952	anterior/posterior pattern specification
GO:0016265	death
GO:0036342	post-anal tail morphogenesis
GO:0042755	eating behavior
GO:0043583	ear development
GO:0043588	skin development
GO:0045198	establishment of epithelial cell apical/basal polarity
GO:0048339	paraxial mesoderm development
GO:0048644	muscle organ morphogenesis
GO:0048705	skeletal system morphogenesis
GO:0050884	neuromuscular process controlling posture
GO:0060231	mesenchymal to epithelial transition
GO:1901311	regulation of gene expression involved in extracellular matrix organization