Version 5.4
Homo sapiens Protein: SLC35G1
Summary
InnateDB Protein IDBP-382761.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC35G1
Protein Name solute carrier family 35, member G1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000400932
InnateDB Gene IDBG-83001 (SLC35G1)
Protein Structure
UniProt Annotation
Function May play a role in intracellular calcium sensing and homeostasis. May act as a negative regulator of plasma membrane calcium-transporting ATPases preventing calcium efflux from the cell. {ECO:0000269PubMed:22084111}.
Subcellular Localization Cell membrane {ECO:0000269PubMed:22084111}; Multi-pass membrane protein {ECO:0000269PubMed:22084111}. Endoplasmic reticulum membrane {ECO:0000269PubMed:22084111}; Multi-pass membrane protein {ECO:0000269PubMed:22084111}. Note=Translocates from the endoplasmic reticulum to the cell membrane in response to a depletion of intracellular calcium and is detected at punctae corresponding to junctions between the endoplasmic reticulum and the cell membrane.
Disease Associations
Tissue Specificity Ubiquitously expressed. {ECO:0000269PubMed:22084111}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000620 Drug/metabolite transporter
PFAM PF00892
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2M3R5
PhosphoSite PhosphoSite-Q2M3R5
TrEMBL
UniProt Splice Variant
Entrez Gene 159371
UniGene Hs.743571
RefSeq NP_001128130
HUGO HGNC:26607
OMIM
CCDS CCDS44459
HPRD 15531
IMGT
EMBL AK091309 AL138923 BC041432 BC104814
GenPept AAH41432 AAI04815 BAC03633 CAH73399

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca