Version 5.4
Homo sapiens Protein: MUTYH
Summary
InnateDB Protein IDBP-383140.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MUTYH
Protein Name mutY homolog (E. coli)
Synonyms MYH;
Species Homo sapiens
Ensembl Protein ENSP00000408176
InnateDB Gene IDBG-97893 (MUTYH)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 16 [view]
Protein-Protein 15 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0006281 DNA repair
GO:0006284 base-excision repair
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR003265 HhH-GPD domain
IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif
IPR011257 DNA glycosylase
IPR015797 NUDIX hydrolase domain-like
PFAM PF00730
PF10576
PRINTS
PIRSF
SMART SM00478
SM00525
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q8TDZ3
UniProt Splice Variant
Entrez Gene 4595
UniGene Hs.271353
RefSeq NP_001121897
HUGO HGNC:7527
OMIM 604933
CCDS
HPRD 05380
IMGT
EMBL AB048788 AL359540 CH471059 HQ205466 HQ205468 HQ205469 HQ205470 HQ205472 HQ205473 HQ205474 HQ205475 HQ205476 HQ205477 HQ205479 HQ205480 HQ205481 HQ205482 HQ205483 HQ205484 HQ205485 HQ205486 HQ205487 HQ205488 HQ205489 HQ205490 HQ205491 HQ205492 HQ205493 HQ205494 HQ205495 HQ205496 HQ205497 HQ205498 HQ205499 HQ205500 HQ205501 HQ205502 HQ205503 HQ205505
GenPept ADP90936 ADP90946 ADP90951 ADP90956 ADP90966 ADP90971 ADP90976 ADP90981 ADP90986 ADP90991 ADP91001 ADP91006 ADP91011 ADP91016 ADP91021 ADP91026 ADP91031 ADP91036 ADP91041 ADP91046 ADP91051 ADP91056 ADP91061 ADP91066 ADP91071 ADP91076 ADP91081 ADP91086 ADP91091 ADP91096 ADP91101 ADP91106 ADP91111 ADP91116 ADP91121 ADP91131 BAB86886 EAX06998 EAX07000

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca